Table 4.

Pre- to post-treatment changes in functional connectivity from whole brain PPI analyses using right and left amygdala seed regions (contrast: ‘Post (Affect Label – Gender Label) - Pre (Affect Label – Gender Label)’). Results are presented for: i) pre- to post-treatment changes, ii) pre- to post-treatment changes correlated with symptom reduction across all groups, iii) group differences in functional connectivity pre- to post-treatment. There were no significant suprathreshold clusters for left or right amygdala seed regions for the comparisons: CBT > WL, ACT > WL, WL > ACT , CBT > ACT or ACT > CBT.

Amygdala seed (L/R)	Anatomical region	Brodmann’s Area	MNI coordinates: x,y,z			t	k
Pre-Post changes in functional connectivity
R	Visual cortex	17/18	21	−82	10	4.24	94
R	Parietal lobe/angular gyrus	40/39	−57	−55	25	3.68	45
R	Primary motor cortex	6	33	14	22	4.86	58
R	Parietal cortex	7	−21	−79	43	3.99	24 4
All groups (Post-Pre) correlation with change in LSAS-SR (Post-Pre)
R	vlPFC	45	48	38	7	4.05	48
L	vmPFC	10/11	−6	26	−14	5.15	54
L	Supplementary motor area	32	6	5	49	− 4.11	68
WL (Post-Pre) > CBT(Post-Pre)
R	Inferior temporal gyrus	19	42	−67	10	4.08	46
L	dlPFC	8/9	−36	26	23	5.00	59