B6.Apc+/+ and B6.ApcMin/+ mice were fed the LFDCoco or HFDCoco for 30 days. Levels of anti- and pro-inflammatory mediators implicated in metabolic syndrome and cancer were measured in the blood (A–F), adipose tissue (G, H), and intestinal tissue (I–L) at day 30 of treatment. Values represent means ± s.e.m. (n=5–7 males/group). *P<0.05, **P<0.01, ***P<0.001 in relation to the same strain fed the LFDCoco. ##P<0.01 in relation to B6.Apc+/+ fed HFDCoco.