View full-text article in PMC IEEE Trans Nucl Sci. Author manuscript; available in PMC: 2017 Feb 28. Published in final edited form as: IEEE Trans Nucl Sci. 2009 Nov 6;5(6):2777–2788. doi: 10.1109/TNS.2009.2024677 Search in PMC Search in PubMed View in NLM Catalog Add to search Copyright and License information PMC Copyright notice TABLE I. Summary of the Pixelation Density Functions Compared PDF Formulations Note D 1 D1∣j={int{logsmax[Qj,j=1,…,N]Qj},whenj∉ℜ0,otherwise} PDF depends on the weighted correlation between the responses of the system to gamma ray emissions in the target-region and in other regions. Defined based on FIM. D 2 D2∣j={int{logsmax[Qj⋅(1∕rjt),j=1,…,N]Qij⋅(1∕rjt)},whenj∉ℜ0,otherwise} PDF depends on both FIM and how far a pixel is from the center of a target-region. More aggressive in reducing the number of pixels in object space. D 3 D3∣j={int{logsmax[1∕rjt],j=1,…,N1∕rjt},whenj∉ℜ0,otherwise} PDF depends on the linear distance r only. Emphasize the importance of the target-region only, without considering the correlation with other regions in the object-space.