Table 2. Pearson correlation coefficient between ER and various measures of LUTS.
Age | PSA | E | T | E/T | PVR | PS | Qmax | IPSS | SERα | EERα | EERβ | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PSA | 0.043 | |||||||||||
E | −0.202 | 0.337* | ||||||||||
T | −0.122 | 0.234 | 0.095 | |||||||||
E/T | −0.108 | 0.025 | 0.571** | −0.678** | ||||||||
PVR | −0.057 | −0.107 | 0.028 | −0.172 | 0.162 | |||||||
PS | 0.257 | 0.588** | 0.475** | 0.229 | 0.107 | 0.093 | ||||||
Qmax | 0.029 | 0.245 | 0.079 | 0.010 | 0.015 | −0.064 | 0.006 | |||||
IPSS | 0.018 | −0.023 | 0.140 | 0.153 | −0.027 | 0.095 | 0.432** | −0.381** | ||||
SERα | 0.368* | 0.321* | 0.238 | 0.105 | 0.067 | 0.037 | 0.514** | −0.163 | 0.324* | |||
EERα | 0.040 | 0.207 | 0.526** | −0.068 | 0.439** | 0.095 | 0.377* | 0.285 | −0.004 | 0.246 | ||
EERβ | −0.142 | 0.207 | 0.555** | 0.262 | 0.140 | −0.007 | 0.219 | 0.138 | −0.066 | 0.103 | 0.251 | |
SERβ | −0.102 | 0.115 | 0.080 | 0.112 | 0.234 | 0.002 | 0.183 | −0.234 | −0.090 | 0.124 | 0.111 | 0.176 |
ER, estrogen receptors; LUTS, lower urinary tract symptoms; PSA, prostate-specific antigen; E, serum estradiol; T, serum total testosterone; E/T, serum estradiol/total testosterone ratio; PVR, postvoid residual volume; PS, prostate size; Qmax, maximal flow rate; IPSS, International Prostate Symptom Score; SERα, stromal estrogen receptor alpha level; EERα, epithelial estrogen receptor alpha level; EERβ, epithelial estrogen beta level.
A p-value <0.05 was considered statistically significant.
*p<0.05. **p<0.01.