Table 1. Characteristics of 1274 men without pre-existing CVD or heart failure, by quartile of minutes per day spent in MVPA.
| Quartile of MVPA (minutes/day) | |||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||||
| Mean (SE) or % (n) | 0.4 – <3.1a | ≥3.1 - <30.8a | ≥30.8 – <53.5 a | ≥53.5 a | P (trend) | all men | N |
| Na | 291 | 308 | 340 | 335 | 1274 | ||
| Age (years) , mean (SE) | 81.0 (5.0) | 78.7 (4.7) | 77.8 (4.0) | 76.5 (3.5) | <0.0001 | 78.4 (4.6) | 1274 |
| Manual Social class,% (n) | 52 (150) | 45 (139) | 45 (154) | 46 (151) | 0.29 | 47 (594) | 1266 |
| Lives alone, % (n) | 23 (65) | 19 (59) | 19 (62) | 16 (52) | 0.18 | 19 (238) | 1256 |
| Smoker, % (n) | 6.6 (19) | 4.6 (14) | 1.5 (5 | 2.1 (7) | 0.002 | 3.5 (45) | 1257 |
| Taking statins, % (n) | 54 (156) | 44 (136) | 44 (150) | 39 (129) | 0.002 | 45 (571) | 1274 |
| Taking anti-hypertensives % (n) | 66 (192) | 54 (167) | 55 (187) | 43 (144) | <0.0001 | 54 (690) | 1273 |
| Taking anticoagulants, % (n) | 7.9 (23) | 6.5 (20) | 4.1 (14) | 4.2 (14) | 0.1 | 5.6 (71) | 1274 |
| Diabetic, % (n) | 22 (63) | 11 (33) | 14 (49) | 10 (34) | <0.0001 | 14 (179) | 1273 |
| Alcohol (units per week) | 5.2 (7.3) | 6.0 (7.7) | 6.8 (7.5) | 7.2 (7.9) | <0.0001 | 6.4 (7.6) | 1240 |
| BMI (kg/m2) | 23.2 (4.6) | 27.4 (3.6) | 26.9 (3.6) | 26.1 (3.1) | <0.0001 | 27.1 (3.8) | 1263 |
| IL-6 (pg/mL)b | 4.30 (2.15) | 3.00 (1.88) | 2.64 (1.99) | 2.50 (2.09) | <0.0001 | 2.99 (2.08) | 1195 |
| CRP (mg/L)b | 2.16 (3.40) | 1.39 (2.98) | 1.23 (3.15) | 0.97 (3.12) | <0.0001 | 1.34 (3.26) | 1183 |
| tPA (ng/mL)b | 10.06 (1.55) | 9.33 (1.52) | 8.77 (1.54) | 8.26 (1.57) | <0.0001 | 9.03 (1.55) | 1190 |
| vWF (IU/dL)b | 129.80 (1.59) | 117.65 (1.58) | 113.94 (1.61) | 110.42 (1.63) | <0.0001 | 117.22 (1.61) | 1190 |
| D-dimer (ng/mL)b,c | 314.11 (1.94) | 228.49 (1.79) | 228.02 (1.80) | 198.83 (1.69) | <0.0001 | 235.59 (1.84) | 1125 |
| IGF-1 (ng/ml) | 72.77 (24.12) | 75.70 (22.45) | 77.11 (23.88) | 78.06 (23.08) | 0.006 | 76.08 (23.63) | 1185 |
| accelerometer wear time (mins/day) | 826 (71) | 850 (63) | 863 (65) | 876 (64) | <0.0001 | 855 (68) | 1274 |
| total activity (counts per day) | 61,669 (24,590) | 113,645 (23.416) | 171,554 (29,976) | 294,370 (83,994) | <0.0001 | 164,749 (99,272) | 1274 |
| steps / day | 1895 (883) | 3645 (832) | 5302 (1022) | 8401 (2370) | <0.0001 | 4,938 (2,794) | 1274 |
| SB (mins/day)d | 676 (76) | 638 (65) | 607 (68) | 552 (76) | <0.0001 | 616 (84) | 1274 |
| LPA (mins/day)d | 144 (56) | 189 (50) | 214 (52) | 239 (61) | <0.0001 | 199 (65) | 1274 |
| MVPA (mins/day)d | 7 (22) | 22 (5) | 41 (6) | 85 (27) | <0.0001 | 40 (33) | 1274 |
Pearson chi square test used for all categorical variables except smoking for which Fisher’s exact test was used
BMI, body mass index
SB, sedentary behaviour
LPA, light physical activity
MVPA, moderate and vigorous physical activity
CRP, C-reactive protein
IL-6, interleukin 6
tPA, tissue plasminogen activator
vWF, von Willebrand factor
IGF-1, insulin-like growth factor
a
maximum N in quartile, varies slightly with missing covariate data
b
geometric means given
c
Men taking anticoagulants excluded