Table 3. Cross-sectional associations between bouts of physical activity, sedentary time, and inflammatory markers.
| ln IL6 | N=1139 | ln CRP | N=1129 | ln TPA | N=1133 | ln VWF | N=1133 | ln DDIMER | N=1070a | IGF | N=1131 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % difference | (95% CI) | % difference | (95% CI) | % difference | (95% CI) | % difference | (95% CI) | % difference | (95% CI) | % difference | (95% CI) | |
| Model 1 | ||||||||||||
| MVPA mins in bouts 1-9 mins | -0.34 | (-0.54, -0.13) | -0.35 | (-0.69, -0.01) | -0.22 | (-0.34, -0.09) | -0.09 | (-0.23, 0.05) | -0.12 | (-0.29, 0.05) | 1.4 | (-5.5, 8.4) |
| MVPA mins in bouts 10+ mins | -0.28 | (-0.57, 0.01) | -0.90 | (-1.38, -0.42) | -0.21 | (-0.39, -0.04) | -0.18 | (-0.37, 0.01) | -0.28 | (-0.52, -0.05) | 1.6 | (-8.1, 11.3) |
| p, Wald test | 0.80 | 0.11 | 0.90 | 0.55 | 0.31 | 0.83 | ||||||
| Model 2 | ||||||||||||
| LIPA mins in bouts 1-9 mins | -0.24 | (-0.35, -0.13) | -0.13 | (-0.33, 0.06) | -0.14 | (-0.21, -0.07) | -0.03 | (-0.10, 0.05) | -0.04 | (-0.14, 0.05) | -1.0 | (-4.8, 2.8) |
| LIPA mins in bouts 10+ mins | -0.07 | (-0.35, 0.21) | -0.26 | (-0.73, 0.21) | 0.04 | (-0.13, 0.21) | -0.02 | (-0.21, 0.17) | 0.16 | (-0.07, 0.40) | -0.3 | (-9.7, 9.2) |
| p, Wald test | 0.37 | 0.66 | 0.05 | 0.87 | 0.19 | 0.88 | ||||||
| Model 3 | ||||||||||||
| SB mins in bouts 1-15 mins | 0.19 | (0.05, 0.32) | 0.32 | (0.10, 0.55) | 0.07 | (-0.01, 0.15) | 0.06 | (-0.03, 0.15) | 0.05 | (-0.06, 0.16) | -1.0 | (-5.6, 3.6) |
| SB mins in bouts 16-30 mins | 0.14 | (0.00, 0.28) | 0.09 | (-0.14, 0.33) | 0.11 | (0.02, 0.19) | 0.06 | (-0.03, 0.15) | 0.07 | (-0.04, 0.19) | -1.4 | (-6.2, 3.3) |
| SB mins in bouts 31-60 mins | 0.14 | (0.04, 0.24) | 0.22 | (0.05, 0.39) | 0.12 | (0.06, 0.18) | 0.04 | (-0.03, 0.10) | -0.03 | (-0.12, 0.05) | 1.5 | (-2.0, 4.9) |
| SB mins in bouts 61+ mins | 0.20 | (0.13, 0.28) | 0.24 | (0.11, 0.37) | 0.07 | (0.02, 0.11) | 0.04 | (-0.01, 0.09) | 0.06 | 0.00, 0.13) | -0.6 | (-3.2, 2.0) |
| p, Wald test | 0.60 | 0.56 | 0.39 | 0.88 | 0.27 | 0.66 | ||||||
Estimates provided are percentage differences (95% CI) in biomarker levels per minute increase in physical activity or sedentary time in specified bout length, derived from linear regression analyses
a
Men taking anticoagulants excluded
All coefficients adjusted for average daily accelerometer wear time, season of wear, region of residence, age, social class, living alone, tobacco and alcohol consumption.
SB, sedentary behaviour
LPA, light physical activity
MVPA, moderate and vigorous physical activity
CRP, C-reactive protein
IL-6, interleukin 6
tPA, tissue plasminogen activator
vWF, von Willebrand factor
IGF-1, insulin-like growth factor
Wald test for coefficients equal to each other