Table 5.

Differentially methylated CpG sites in neural tissues of fetal mice with and without BaP exposure during ED 7.0–10.5^a.

	Controls (1)		Normal neural tube fetus with BaP exposure (2)		NTD fetus with BaP exposure (3)		Difference between (3) and (1)	Difference between (3) and (2)	Difference between (1) and (2)
CpG sites	Mean	SD	Mean	SD	Mean	SD	P-value	P-value	P-value	P for trend
Ctnna1_CpG_1	0.83	0.09	0.89	0.10	0.92	0.08	0.034	0.460	0.172	0.033
Ctnna1_CpG_2	0.40	0.10	0.45	0.06	0.48	0.06	0.027	0.533	0.132	0.026
Ctnna1_CpG_3	0.80	0.11	0.87	0.05	0.87	0.05	0.061	0.980	0.065	0.057
Ctnna1_CpG_4	0.40	0.10	0.45	0.06	0.48	0.06	0.027	0.533	0.132	0.026
Ctnna1_CpG_5	0.63	0.09	0.69	0.11	0.75	0.08	0.008	0.212	0.152	0.008
Ctnna1_CpG_6.7	0.57	0.10	0.62	0.10	0.69	0.07	0.013	0.137	0.313	0.013
Ctnna1_CpG_8	0.40	0.11	0.44	0.08	0.52	0.06	0.007	0.076	0.363	0.008
Ctnna1_CpG_9	0.51	0.10	0.58	0.11	0.68	0.11	0.002	0.081	0.171	0.003
Ctnna1_CpG_10	0.46	0.16	0.57	0.12	0.65	0.09	0.003	0.186	0.079	0.003
Ctnna1_CpG_11.12	0.60	0.09	0.62	0.14	0.67	0.09	0.151	0.353	0.627	0.151
Ctnna1_CpG_13	0.63	0.13	0.76	0.14	0.80	0.11	0.007	0.555	0.032	0.006
Myh2_3_CpG_1	0.77	0.10	0.71	0.17	0.81	0.08	0.429	0.094	0.346	0.429
Myh2__3_CpG_2	0.50	0.03	0.53	0.09	0.57	0.09	0.072	0.335	0.406	0.072
Myh2__3_CpG_4	0.34	0.03	0.38	0.02	0.42	0.07	0.001	0.072	0.061	0.001
Myh2__3_CpG_5	0.54	0.05	0.61	0.04	0.64	0.08	0.001	0.344	0.013	0.001
Myh2__3_CpG_6	0.33	0.04	0.36	0.07	0.38	0.06	0.076	0.521	0.261	0.076

^aIndependent Samples Test.