Fig 5. NSAID-induced decrease in anti-apoptosis proteins is associated with increased caspase activity.

Caspase 3/7activity in muscle homogenates from saline- and NSAID-treated animals (4/group) was measured at 54 hrs after injury (7 hrs post-treatment) by commercial ELISA. Data are given as the fold-change for each animal relative to its own non-injured TA muscle. Responses between saline versus NSAID-treated animals were statistically significant as determined by ANOVA using a mixed model with random effect of animal within treatment with the level of significance set at p < .05.