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. 2017 Feb 28;12(2):e0173112. doi: 10.1371/journal.pone.0173112

Fig 2. Scheme for calculations of regional, segmentation-based subtractions (sFV, upper row) and absolute changes of tumor volume (dFV, lower row).

Fig 2

The FLAIR segmentation of the baseline MRI is referred to as FV1, the segmentation of the follow-up MRI as FV2. For regional, segmentation-based subtractions (sFV) a voxel-wise subtraction was performed. Only overlapping voxels of FV1 and FV2 were subtracted. For the absolute change of tumor volume the total change of volume between FV2 and FV1 was calculated by subtraction.