Table 4. Associated replicon types and addiction systems in Enterobacteriaceae plasmids.
| Replicon | Associated addiction systems | Associated resistance genes | Source/Reference |
|---|---|---|---|
| IncF | pemIK, ccdAB, hok-sok, vagCD | blaCTX-M, blaKPC, blaCMY-2-like, blaDHA | [20, 21, 48, 49] |
| IncL/M | pemIK | blaIMP, blaCTX-M, blaTEM | [20, 21, 40] |
| IncI1 | pndBCA, relE-RHHa (in some) | blaCMY-2-like, blaCTX-M, blaTEM | [20–22] |
| IncA/C | relE-vapIa | blaCMY-2-like, blaNDM, blaSHV, blaVEB | |
| IncHI2 | vagCD | blaCTX-M, blaSHV | [21] |
| IncN | stbBC | blaKPC, blaCTX-M, blaSHV | [50, 51] |
| IncX | hicA-hicB-like (in some) | blaCTX-M, blaKPC, blaNDM | [52–55] |
a putative systems identified using RASTA-Bacteria (http://genoweb1.irisa.fr/duals/RASTA-Bacteria/) and TA-finder (http://202.120.12.133/TAfinder/TAfinder.php).