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. 2017 Feb 13;13(2):e1005377. doi: 10.1371/journal.pcbi.1005377

Table 1. Initial values of the ion concentrations, the membrane voltage, IP3 and the fraction of the activated IP3 receptor channels.

For the calculation of [Ca2+]ER, [IP3]i and h see Model section Model parameter values.

Parameter Value Source
[Ca2+]i 0.073 μM [23]
[Ca2+]ER 25 μM see text
[Ca2+]o 1800 μM [18]
[Na+]i 15 mM [19]
[Na+]o 145 mM [19]
[K+]i 100 mM [19]
[K+]o 3 mM [19]
V -85 mV [24]
[IP3]i 0.15659 μM see text
h 0.7892 see text