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Encapsulation of different enzyme–DNA hybrids inside CCMV capsids (gray) at pH 7.5. Encapsulation of (A) ssDNA in yellow, (B) GOx, in blue, functionalized with ssDNA, (C) GCK, in green, functionalized with the complementary ssDNA in red, (D) GOx conjugated to GCK. The specific sequence of ssDNA is catalytically active in the presence of hemin.
