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. 2017 Jan 5;139(4):1512–1519. doi: 10.1021/jacs.6b10948

Figure 3.

Figure 3

Purification and characterization of enzyme-filled CCMV capsids. Size-exclusion chromatograms for CCMV containing (A) ssDNA, (B) GOx–ssDNA, (C) GCK–csDNA, and (D) GOx–GCK, with monitoring at λ = 260 (red), 280 (blue), and 450 nm (black), for DNA, CCMV, and flavin (GOx), respectively. The schematic cartoons above each peak represent the corresponding particles. Negatively stained transmission electron microscopy of (E) ssDNA, (F) GOx–ssDNA, (G) GCK–csDNA, and (H) GOx–GCK encapsulated CCMV assemblies.