Figure 2. Human MSCs grown in the presence of heparin exhibited an altered gene expression signature.
Human MSCs were serially passaged with or without 160 ng/ml heparin. Gene expression signatures of hMSCs at P4, P6 and P8 were obtained using a stem cell-related chemiluminescent cDNA array. Expression profiles were analyzed by (A) singular value decomposition, or (B and C) hierarchical clustering and Pearson correlation distance/similarity approaches.