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. 2017 Jan 30;127(3):830–842. doi: 10.1172/JCI87583

Figure 5. Oncogenic functions of E2f1 and E2f3b are cell autonomous.

Figure 5

(A) Box plots showing the liver/body weight of 12- to 18-month-old male mice in which the knockin allele or alleles have been deleted in hepatocytes or macrophages using Alb-Cre or Lys-Cre, respectively. Wilcoxon method with Bonferroni’s correction for multiple tests. *P < 0.001 vs. control. (B) Histopathological classification of livers from A. Fisher’s exact tests with Bonferroni’s correction. ‡P = 0.001, carcinoma vs. control. (C) Box plots showing the liver/body weight of 12- to 18-month-old female mice. Wilcoxon method with Bonferroni’s correction. *P < 0.012 vs. control. (D) Histopathological classification of livers from C. Fisher’s exact tests with Bonferroni’s correction. ‡P = 0.001, carcinoma vs. control.