Figure 1. LTB4R1 expression pattern in various tissue-resident B2 cells.
(A) The population of the B cell subsets B1 cell (CD19+CD5+) and B2 cell (CD19+CD5–) in VAT of LFD- and HFD-fed WT mice, shown quantitatively to the right. (B and C) GTTs and ITTs of HFD-fed Bnull and WT mice. (D and E) Gene expression of Ltb4r1 and its protein level in spleen and VAT B2 cells of HFD-fed WT mice. Data are presented as mean ± SEM. n = 6 per group (A–E). *P < 0.05, **P < 0.01, ***P < 0.001, Student’s t test (A, D, E); 1-way ANOVA with Bonferroni’s post test (B and C).