Table 3. The univariate and multivariate analysis between EPC population and endothelial function, CIMT, inflammatory markers, and clinical characteristics in the patients with AS.
| Variables | Univariate analysis | Multiple regression analysis | ||
|---|---|---|---|---|
| r | p Value | Correlation β coefficient | p Value | |
| EPC | ||||
| Age | −0.220 | 0.258 | ||
| Duration of AS | −0.580 | 0.001 | −1.611 | 0.124 |
| BASDAI | −0.438 | 0.01 | 0.522 | 0.608 |
| BASFAI | −0.458 | 0.01 | 0.150 | 0.150 |
| ESR | −0.060 | −0.730 | ||
| CRP | −0.540 | 0.003 | −2.379 | 0.028 |
| FMD % | 0.870 | 0.001 | 3.858 | 0.001 |
| CIMT | −0.767 | < 0.001 | −1.851 | 0.042 |
| TNF-α | −0.847 | 0.001 | −3.458 | 0.003 |
| IL-6 | −0.818 | 0.001 | −1.151 | 0.264 |
| IL-1 | −0.214 | 0.273 | ||
Abbreviations: BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; CIMT, carotid intima-media thickness; CRP, C-reactive protein; EPC, endothelial progenitor cells; ESR, erythrocyte sedimentation rate; FMD, flow-mediated dilatation; IL-1, interleukin-1; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α.
Note: Multivariate analysis was only performed for univariate result at p-value < 0.01.
Values in bold indicate, p-value < 0.05.