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. 2017 Feb 6;127(3):888–898. doi: 10.1172/JCI88508

Figure 6. Focal amplifications in Rb/TET-MYCN DOX-independent tumors.

Figure 6

CNV profiles of samples harboring focal amplifications in (A) Mycn or (B) Mir-17-92. Low-coverage whole-genome sequencing data were analyzed using CNVSeq. Arrows point to focal amplifications. chr, chromosome. (C) Integrative Genomics Viewer (IGV) (http://software.broadinstitute.org/software/igv/) plot showing the genomic regions of Mycn and Mir-17-92 amplification.