Table 1. Characteristics of 162 Patients With Type 2 Diabetes and Correlation Coefficients of Maximum Carotid IMT (Age- and Sex-Adjusted) and SD-LDLC.
| Overall (n = 162) | Correlation coefficients |
|||
|---|---|---|---|---|
| Maximum IMT | SD-LDLC | |||
| Male sex (n, %) | 89 (54.9) | -0.17* | Adjusted | 0.159* |
| Age (years) | 62 ± 10 | 0.29*** | Adjusted | -0.14 |
| Smokers (n, %) | 53 (32.7) | 0.06 | -0.01 | 0.04 |
| BMI (kg/m2) | 24.2 ± 3.7 | -0.02 | 0.05 | 0.06 |
| Waist circumference (cm) | 87.0 ± 10.0 | 0.07 | 0.12 | 0.2** |
| Duration of diabetes (years) | 9.7 ± 7.2 | 0.10 | -0.01 | 0.01 |
| Treatment of diabetes | ||||
| Diet/OHA/insulin (n, %) | 53/81/28 (33/50/17) | -0.01 | -0.02 | -0.03 |
| Users of CCB/RASi/diuretics (n, %) | 56/68/7 (35/42/4) | 0.15 | 0.10 | -0.06 |
| Users of hypolipidemic drugs (n, %) | 70 (43.2) | 0.17* | 0.22** | 0.26*** |
| HbA1c (%) | 7.0 ± 0.8 | 0.13 | 0.10 | 0.01 |
| Fasting PG (mg/dL) | 125 ± 23 | 0.03 | 0.00 | 0.02 |
| Post-breakfast PG (mg/dL) | 154 ± 48 | 0.06 | 0.01 | -0.11 |
| CV-HbA1c (%) | 6.7 ± 5.7 | -0.04 | 0.01 | 0.25*** |
| Total cholesterol (mg/dL) | 188 ± 21 | 0.02 | 0.11 | 0.27*** |
| LDLC (mg/dL) | 112 ± 22 | 0.12 | 0.19* | 0.28*** |
| SD-LDLC (mg/dL) | 15 ± 10 | 0.10 | 0.21* | 1 |
| HDLC (mg/dL) | 55 ± 15 | -0.18* | -0.13 | -0.07 |
| Fasting TG (mg/dL) | 114 ± 51 | 0.07 | 0.07 | 0.21** |
| Post-breakfast TG (mg/dL) | 145 ± 62 | 0.01 | -0.05 | 0.13 |
| Serum creatinine (mg/dL) | 0.8 ± 0.2 | 0.18* | 0.03 | -0.16* |
| eGFR (mL/min/1.73 m2) | 76 ± 16 | -0.13 | 0.01 | 0.18* |
| Uric acid (mg/dL) | 5.2 ± 1.3 | 0.10 | 0.03 | -0.12 |
| Systolic BP (mm Hg) | 128 ± 12 | 0.13 | 0.09 | 0.06 |
| SD-systolic BP (mm Hg) | 8.1 ± 2.2 | 0.20* | 0.15 | -0.01 |
| Diastolic BP (mm Hg) | 72 ± 6 | 0.00 | 0.08 | 0.12 |
| Urinary ACR (mg/g) | 86 ± 327 | 0.01 | -0.01 | 0.06 |
| Log ACR | 1.3 ± 0.6 | 0.23** | 0.18* | 0.06 |
| Leucocyte count (103/μL) | 5.8 ± 1.5 | 0.05 | 0.03 | 0.14 |
| Maximum IMT (mm) | 1.04 ± 0.30 | 1 | 1 | 0.10 |
| Mean IMT (mm) | 0.83 ± 0.18 | 0.93*** | 0.92*** | 0.05 |
| ACR ≥ 30 mg/g (n, %) | 53 (32.7) | 0.20* | 0.15 | 0.034 |
| eGFR < 60 mL/min/1.73 m2) | 25 (15.4) | 0.11 | 0.03 | -0.12 |
| Chronic kidney disease (n, %) | 66 (40.7) | 0.18* | 0.10 | 0.00 |
Mean ± SD or n, %. SD-LDLC: standard deviation of low-density lipoprotein cholesterol; OHA: oral hypoglycemic agents; CCB: calcium channel blockers; RASi: renin-angiotensin system inhibitors; PG: plasma glucose; CV: coefficient of variation; eGFR: estimated glomerular filtration rate; BP: blood pressure; ACR: albumin/creatinine ratio; IMT: intima-media thickness. *P < 0.05. **P < 0.01. ***P < 0.001.