Table 1.
Variables | Value |
Male/female | 90/48 (65.2/34.8) |
Median age at diagnosis (IQR) (yr) | 21 (19-27) |
Median age at first infusion (IQR) (yr) | 27 (22-33) |
Median duration of disease prior to first IFX (IQR) (mo) | 52 (13-91) |
Indication for IFX treatment | |
Luminal | 122 (88.4) |
Perianal fistulizing | 16 (11.6) |
Median follow-up of IFX treatment (IQR) (mo) | 47 (30-73) |
Disease location at diagnosis | |
L1 (ileum) | 19 (13.8) |
L2 (colon) | 9 (6.5) |
L3 (ileocolon) | 108 (78.3) |
Not documented | 2 (1.4) |
Disease behavior at diagnosis | |
B1 (non-stricturing non-penetrating) | 115 (83.3) |
B2 (stricturing) | 7 (5.1) |
B3 (penetrating) | 16 (11.6) |
Perianal fistula at diagnosis | |
Active | 36 (26.1) |
Previous | 26 (18.8) |
Smoking status at diagnosis | |
Current smoker | 26 (18.8) |
Ex-smoker | 9 (6.6) |
Never smoker | 103 (74.6) |
Previous major abdominal surgery prior to first IFX | 44 (31.9) |
Concomitant immunomodulators | |
None | 73 (52.9) |
Azathioprine/6-mercaptopurine | 64 (46.4) |
Methotrexate | 1 (0.7) |
IQR: Interquartile range; IFX: Infliximab.