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. 2017 Jan 25;595(5):1815–1829. doi: 10.1113/JP273404

Figure 9. Numbers of backlabelled common peroneal (CP) motoneurons that regenerated their nerves after sciatic nerve transection and resuture in C57BL/6‐Smn +/− transgenic and C57BL/6‐wild type control mice.

Figure 9

Left CP nerves served as intact internal controls. The right sciatic nerves of 4‐month‐old mice were cut and subsequently repaired (coapted) by direct suture of the proximal and distal stumps. Three weeks later, left control and the right axotomized CP motoneurons were backlabelled via the CP nerve at sites that were distal to the repair site of the right CP nerve. Motoneuron counts were completed on 20 μm thick longitudinal spinal cord sections between T11 and L2; every second section was counted through the entire spinal cord. Data are corrected for thickness of the longitudinal sections. Each bar represents the mean (±SEM) of data obtained from 8 C57BL/6‐Smn +/− transgenic and 7 C57BL/6‐wild type mice. The corrected motoneuron counts after right CP nerve regeneration were significantly different from counts from the left intact CP nerves but the counts were not different between the Smn +/− transgenic and the wild type mice.