Figure 3. Anti‐oxidant mechanisms and NO bioavailability.
Values are means ± SEM at day 19 of the expression of SOD (A), the activity of catalase (B), the expression of GPx (C), and the concentration of NOx (D) in the heart of chick embryos incubated in either N, H, HS or NS (n = 9, 9, 8, 8, respectively, for A and B; n = 6 for all groups for C; n = 8, 8, 9, 9, respectively, for D). Significant (P < 0.05) differences are: *effect of hypoxia (N vs. H and NS vs. HS); †effect of sildenafil (N vs. NS and H vs. HS); two‐way ANOVA with no interaction (A, B and C) or with interaction and Bonferroni post hoc test (D).