Table 1.
Brachial artery diameter, shear and flow‐mediated dilatation data during baseline and post‐maximal exercise at sea level and high altitude
| Sea level | High altitude | |||
|---|---|---|---|---|
| Baseline | Post‐max | Baseline | Post‐max | |
| Diameter (mm) | 4.4 ± 0.2 | 4.2 ± 0.2* | 4.3 ± 0.2 | 3.9 ± 0.2* |
| Time: P = 0.004, Altitude: P = 0.030, Interaction: P = 0.328 | ||||
| Mean shear (s−1) | 86.4 ± 13.5 | 297.6 ± 26.2* , † | 111.8 ± 20.1 | 213.5 ± 27.7* |
| Time: P < 0.001, Altitude: P = 0.244, Interaction: P = 0.003 | ||||
| Antegrade shear (s−1) | 101.7 ± 13.7 | 337.9 ± 20.5* , † | 144.5 ± 17.3 | 308.3 ± 24.3* , † |
| Time: P < 0.001, Altitude: P = 0.833, Interaction: P = 0.012 | ||||
| Retrograde shear (s−1) | ‐15.2 ± 6.2 | −40.5 ± 8.6* | −22.1 ± 7.1 | −89.6 ± 14.9* |
| Time: P = 0.001, Altitude: P = 0.031, Interaction: P = 0.009 | ||||
| Change in diameter (mm) | 0.23 ± 0.05 | 0.25 ± 0.05 | 0.26 ± 0.04 | 0.32 ± 0.05 |
| Time: P = 0.453, Altitude: P = 0.380, Interaction: P = 0.581 | ||||
| FMD (%) | 5.0 ± 1.1 | 6.2 ± 1.2 | 6.3 ± 1.3 | 8.5 ± 1.6 |
| Time: P = 0.282, Altitude: P = 0.244, Interaction: P = 0.532 | ||||
| FMD SRAUC (103 s−1) | 23.3 ± 1.9 | 30.3 ± 2.8* | 23.2 ± 2.7 | 22.6 ± 1.9* |
| Time: P = 0.025, Altitude: P = 0.312, Interaction: P = 0.185 | ||||
FMD, flow‐mediated dilatation; SRAUC, shear rate area under the curve.
* P < 0.05, pre‐max data vs. post‐max data.
† P < 0.05, interaction effect baseline vs. post‐max.