Table 2.
Baseline Predictors of Clinical Deterioration at 2- and 4-Month Follow-Up Among Moderately Anxious Patients Assigned to the Watchful Waiting (WW) Cohort at Baseline
| Watchful waiting randomized* (N =23) |
Watchful waiting not randomized* (N = 56) |
P | |
|---|---|---|---|
| Age, mean (SD) | 44.7 (10.2) | 41.1 (11.3) | 0.18 |
| Male, % (N) | 26 (6) | 43 (24) | 0.16 |
| White, % (N) | 74 (17) | 89 (50) | 0.08 |
| African-American, % (N) | 26 (6) | 9 (5) | 0.05 |
| Other, % (N) | 0 (0) | 2 (1) | 0.52 |
| > High school education, % (N) | 70 (16) | 91 (51) | 0.02 |
| Married, % (N) | 65 (15) | 71 (40) | 0.59 |
| Living alone, % (N) | 22 (5) | 16 (9) | 0.55 |
| Working, part-time/full-time, % (N) | 74 (17) | 75 (42) | 0.92 |
| Social Support Scale, mean (SD) | 67.3 (20.7) | 77.2 (19.8) | 0.06 |
| PRIME-MD diagnosis, % (N) | 0.28 | ||
| GAD | 35 (8) | 54 (30) | |
| PD | 35 (8) | 21 (12) | |
| GAD/PD | 30 (7) | 25 (14) | |
| Major depression, % (N)† | 78 (18) | 64 (36) | 0.23 |
| SF-36v2 MCS, mean (SD)§ ‡‡ | 37.3 (7.9) | 38.0 (9.3) | 0.75 |
| SF-36v2 PCS, mean (SD)§ ‡‡ | 49.8 (9.4) | 52.9 (8.7) | 0.18 |
| SIGH-A, mean (SD)║ †† | 19.8 (5.5) | 16.8 (2.8) | 0.02 |
| PDSS, mean (SD)¶ †† | 8.4 (3.9) | 7.3 (4.8) | 0.28 |
| GADSS, mean (SD)# †† | 11.4 (2.8) | 10.8 (2.7) | 0.37 |
| PHQ-9, mean (SD)** †† | 9.8 (4.1) | 9.5 (4.2) | 0.75 |
Abbreviations: GAD, generalized anxiety disorder; GADSS, Generalized Anxiety Disorder Severity Scale; PRIME-MD, Primary Care Evaluation of Mental Disorders; PD, panic disorder; PDSS, Panic Disorder Severity Scale; PHQ-9, 9-item Patient Health Questionnaire; SIGH-A, structured interview guide for the Hamilton Anxiety Rating Scale; SF-36 MCS, Medical Outcomes Study Short Form Mental Component Scale; SF-36 PCS, Medical Outcomes Study Short Form Physical Component Scale
* At baseline, “watchful waiting” patients scored either 14–19 on the SIGH-A or 7–10 on the PDSS and were not in the “high anxiety” range on either measure. Later, we randomized those who scored ≥20 on the SIGH-A or ≥10 on the PDSS at either their 2- or 4-month telephone follow-up assessment
†Determined using Primary Care Evaluation of Mental Disorders (PRIME-MD)
‡Range 11–55
§Range 0–100
║Range 0–56
¶Range 0–28
#Range 0–24
**Range 0–27
††Higher scores indicate more severe symptoms
‡‡Higher scores indicate better health-related quality of life