Table 4.
Proportion of Patients Achieving ≥40 % Decline from Baseline Levels of Anxiety or Mood Symptoms at 12-Month Follow-Up
| High anxiety intervention |
High anxiety usual care |
|||||
|---|---|---|---|---|---|---|
| N | % (N) | N | % (N) | P | NNT (95 % CI)* | |
| SIGH-A | ||||||
| All | 99 | 53 (52) | 108 | 32 (35) | 0.003 | 5 (14, 3) |
| Male | 28 | 71 (20) | 27 | 33 (9) | 0.005 | 3 (7, 2) |
| Female | 71 | 45 (32) | 81 | 32 (26) | 0.10 | 8 (−41, 4) |
| African-American | 21 | 38 (8) | 19 | 16 (3) | 0.16 | 4 (−24, 2) |
| PDSS (PD and PD/GAD cohorts only)† | ||||||
| All | 50 | 70 (35) | 55 | 38 (21) | 0.001 | 3 (7, 2) |
| Male | 16 | 81 (13) | 12 | 25 (3) | 0.006 | 2 (4, 1) |
| Female | 34 | 65 (22) | 43 | 42 (18) | 0.05 | 4 (96, 2) |
| African-American | 10 | 60 (6) | 12 | 17 (2) | 0.07 | 2 (16, 1) |
| GADSS (GAD and PD/GAD cohorts only)† | ||||||
| All | 97 | 49 (48) | 100 | 28 (28) | 0.002 | 5 (12, 3) |
| Male | 27 | 67 (18) | 26 | 31 (8) | 0.009 | 3 (9, 2) |
| Female | 70 | 43 (30) | 74 | 27 (20) | 0.05 | 6 (226, 3) |
| African-American | 21 | 48 (10) | 17 | 6 (1) | 0.01 | 2 (6, 2) |
| PHQ-9 (Major depression cohort only)† | ||||||
| All | 87 | 64 (56) | 98 | 41 (40) | 0.001 | 4 (10, 3) |
| Male | 21 | 76 (16) | 26 | 38 (10) | 0.01 | 3 (9, 2) |
| Female | 66 | 61 (40) | 72 | 42 (30) | 0.03 | 5 (39, 3) |
| African-American | 19 | 58 (11) | 19 | 26 (5) | 0.05 | 3 (55, 2) |