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. 2016 Dec 5;32(3):325–344. doi: 10.1007/s11606-016-3922-9

Table 4.

Studies that Examined Change in Overall Cost

Citation
Study design Methodology rating Program costs Changes in overall costs Costs calculation
Bryant-Stephens and Li 200835 RCT 2 (5) $675 per family per year
Krieger et al. 200555 RCT 4 (5) High intensity calculated cost savings: $201-$334 per child; low intensity cost savings: $185-$315 per child Savings calculated based on visits averted × average cost of visit type
Krieger et al. 201554 RCT 4 (5) $1300 per participant per year
Rothschild et al. 201456 RCT 3 (5) $1020 per participant per year*
Adair et al. 201247 Pre-post Moderate (1) $392 per participant per year* Net savings $103,065 Savings calculated based on visits averted × average cost of visit type
Ferrer et al. 201348 Pre-post Weak (3) 9% decrease in total charges, savings compared with prior year $250,215 Savings calculated based on matched patient utilization in year prior
Margellos-Anast et al. 201241 Pre-post Weak (3) Cost saving $2561.60 per participant. ROI: $5.58 per dollar spent Savings calculated based on visits averted × average cost of visit type
Primomo, et al. 200646 Pre-post Weak (3) $200 per family total*
Bryant-Stephens et al. 200949 Cohort 5 (9) $450-$500 per family total*
Enard and Ganelin 201350 Cohort 7 (9) $45,880 per CHW per year* Mean cost savings ranged per person from $331 to $1,369 depending on frequency of use in year prior to intervention
Felix et al. 201152 Cohort 8 (9) $896,000 total costs* Physician office spending decreased by $266 per person in the intervention, decreased by $49 per person in the comparison.
Cost increased 19.3% over study period intervention compared with 30% increase in case control: total savings per person $1565 in intervention. 23.8% net saving per participant 2005–2008 ($2.619 million)
Johnson et al. 20125 Cohort 7 (9) $559 per participant per year* Accrued participant costs over study period
Intervention group:
Total ED costs $225,324;
Total inpatient costs $183,812;
Total non-narcotics Rx costs $379,970
Total narcotics Rx costs $33,647
Comparison group:
Total ED costs $121,858;
Total inpatient costs $205,144;
Total non-narcotic Rx costs $171,602
Total narcotic Rx costs $9,812
Roth et al. 201258 Cohort 7 (9) No significant savings across total claims (pharmacy, outpatient, inpatient, emergency, lab, home health, long-term care, other)
Brown et al. 201263 Cost-effect 14 (19) $783.75 per participant per year* Incremental cost-effectiveness ratio (ICER): $10,995 to $33,319 per QALY gained ICER calculated using actual costs and Archimedes Model
Kattan et al. 200540 Cost-effect (RCT) 16 (19) $1472 per family total Intervention costs were $1042 greater than control group; service reductions were unable to offset cost. Subgroup analysis yielded no savings ICER curve based on average health care costs per symptom-free day
Mirambeau et al., 201330 Cost-effect 13 (19) $420,640 total program costs*
Ryabov 201464 Cost-effect 13 (19) $824 per participant per year Incremental cost-effectiveness ratio: $13,810 per QALY gained ICER calculated using recorded data CDC Diabetes Cost Effectiveness Model

*Indicates that some program costs, such as salary or benefits, were taken into account in cost reporting

†Indicates that study did not assess significance of reported cost-savings

‡Indicates significance at P < 0.05 level