Table 1.
Strain | Child gender/age | Underlying conditions | 20 antimicrobials tested | GEIs detected | ||
---|---|---|---|---|---|---|
S | I | R | ||||
1197 | Male/8 years | Acute lymphoblastic leukemia | TI, PI, TM, PT, CA, FE, IM, AZ, AM, GE, TO, PO, CI, LO, NO, LE | CB, CT, ME | CR | PAGI-1, PAPI-1, PAPI-2, pKLC102 [2] |
1210 | Female/1 year | Hemophagocytic syndrome | IM, ME, AM, GE, TO, PO, CI, LO, NO, LE | CB, TI, TM, CA, FE, AZ | PI, PT, CR, CT | PAPI-1, PAPI-2 [8] |
1211 | Male/5 years | Aplastic anemia | TI, TM, CA, CR, FE, AZ, AM, GE, TO, PO, CI, LO, NO, LE | CB, PI, CT | PT, IM, ME | PAPI-1, PAPI-2 [8] |
1212 | Female/14 years | Cavernous angioma | TI, PI, TM, PT, CA, CR, CT, FE, IM, ME, AZ, AM, GE, TO, PO, CI, LO, NO, LE | CB | PAPI-1, PAPI-2 [8] | |
1220 | Male/4 years | Osteosarcoma | AM, GE, TO, PO, NO, LE | CB, TI, PI, TM, CA, FE, AZ, CI, LO | PT, CR, CT, IM, ME | PAPI-1, PAPI-2, pKLC102 [5] |
1226 | Male/1 year | Biliary atresia | PO, CI, LO, NO, LE | TI | CB, PI, TM, PT, CA, CR, CT, FE, IM, ME, AZ, AM, GE, TO | PAPI-2 [11] |
1239 | Male/6 years | Acute myeloblastic leukemia | TI, FE, AZ, AM, GE, TO, PO, NO | CB, PI, TM, PT, CA, CI, LO, LE | CR, CT, IM, ME | PAPI-1, PAPI-2 [8] |
1241 | Female/7 years | Epoxy encephalopathy | PO | CB, TI, PI, TM, PT, CA, CR, CT, FE, IM, ME, AZ, AM, GE, TO, CI, LO, NO, LE | PAGI-1, PAPI-1, PAPI-2 [4] |
S, Susceptible; I, Intermediate resistance; R, Resistant. CB, Carbenicillin; TI, Ticarcillin; PI, Piperacillin; TM, Ticarcillin/Clavulanic acid; PT, Piperacillin/Tazobactam; CA, Ceftazidime; CR, Ceftriaxone; CT, Cefotaxime; FE, Cefepime; IM, Imipenem; ME, Meropenem; AZ, Aztreonam; AM, Amikacin; GE, Gentamicin; TO, Tobramycin; PO, Polymyxin B; CI, Ciprofloxacin; LO, Lomefloxacin; NO, Norfloxacin; LE, Levofloxacin. GEIs, Genomic Islands; [number] correspond to GEIs genotype.