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. 2017 Mar 1;8:86. doi: 10.3389/fphys.2017.00086

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Copyright © 2017 Ji, Park, Lee, Park, Son and Hong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential effects of Dex on neurotransmitter inputs and inflammatory mediator-induced intracellular calcium signaling in mouse SMG cells. (A) Changes in [Ca²⁺]_i induced by 100 μM isoproterenol without (closed circle) and with pre-treatment with 100 ng/ml Dex (open square). All of the traces were averaged. (B) Changes in [Ca²⁺]_i induced by 10 μM carbachol without (closed circle) and with pre-treatment with 100 ng/ml Dex (open square). All of the traces were averaged. (C) Changes in [Ca²⁺]_i induced by 100 nM histamine without (closed circle) and with pre-treatment with 100 ng/ml Dex (closed square). All of the traces were averaged. (D) Changes in [Ca²⁺]_i induced by 20 μg/ml LPS in ducts and in acini without (gray line for ducts and light gray line for acini) and with (black line) pre-treatment with 100 ng/ml Dex. A single trace is shown. Arrows indicate when stimuli were applied to the cells.