Fig. 4.

Graph showing the effect of tadalafl and COMB-4 on inducible nitric oxide synthase (iNOS) expression at day 14 and day 42 after femoral osteotomy. The graph shows quatitative image analysis results of the intensity of iNOS expression per cell. Results are expressed as mean and standard error of the mean (* p = 0.043; ** p = 0.002 when compared with control group, using analysis of variance followed by Tukey as post hoc test) (COMB-4: L-citrulline, Paullinia cupana, ginger and muira puama).