Table 2.
JUNQ/INQ | IPOD | Regulates inclusion formation | References | |
---|---|---|---|---|
Hsp104 | x | x | +++ | 16 17 42 43 44 45 47 |
Ssa1/2 | x | x | +++ | 42 46 57 |
Sse1 | nd | nd | +++ | 42 |
Ydj1 | nd | nd | +++ | 42 45 |
Sti1 | nd | nd | + (JUNQ/INQ) | 16 43 |
Sis1 | x | x | ++ (JUNQ/INQ) | 57 72 |
Hsp42 | x | +++ (IPOD) | 17 42 43 57 72 | |
Hsp82 | nd | nd | ++ | 42 |
Mca1 | x | x | − | 45 72 |
Btn2 | x | x | +++ (JUNQ/INQ) | 43 57 72 |
Cur1 | x | + | 57 | |
Vac17 | nd | nd | ++ | 63 |
Hsp26 | x | x | − | 17 42 |
Tsa1 | x | x | − | 38 |
Ltn1 | x | +++ (IPOD) | 69 |
Localization of studied sorting factors and chaperones to quality control sites and the dependence on their presence for proper inclusion formation. Major determinants of spatial sorting denoted with +++, less important factors ++, and factors displaying only a minor role in sorting are denoted with +. Chaperones and aggregate‐associated factors that do not affect spatial sorting are denoted with −. nd, localization in respect to quality control sites has not been determined.