Table 3.
Biochemical parameter | Normal data | Experimental groups | ||||||
---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | ||
AST | 114.5 ± 25.4 | 174 ± 5.4a | 178.5 ± 5.4a | 183 ± 5.4a | 182 ± 5.4a | 181 ± 5.4a | 166.3 ± 5.4a | 172 ± 5.4a |
ALT | 58.5 ± 10.2 | 51.2 ± 1.8ab | 54.6 ± 1.8b | 52.7 ± 1.8ab | 54.3 ± 1.8b | 53.9 ± 1.8ab | 47.1 ± 1.8a | 51 ± 1.8ab |
FAS | 389.7 ± 49.3 | 349 ± 20.53a | 350.2 ± 20.53a | 338.8 ± 20.53a | 363.4 ± 20.53a | 379 ± 20.53a | 359.6 ± 20.53a | 303.7 ± 20.53a |
Glucose | 7.9 ± 0.8 | 7.8 ± 0.26a | 7.7 ± 0.26a | 7.5 ± 0.26a | 7.4 ± 0.26a | 7.3 ± 0.26a | 6.9 ± 0.26a | 7.1 ± 0.26a |
Cholesterol | 2.0 ± 0.5 | 2 ± 0.08ab | 1.83 ± 0.08ab | 2 ± 0.08ab | 2 ± 0.08ab | 2.2 ± 0.08b | 1.9 ± 0.08ab | 1.78 ± 0.08a |
Triglycerides | 0.66 ± 0.16 | 0.9 ± 0.1ab | 0.61 ± 0.1a | 0.72 ± 0.1ab | 0.62 ± 0.1ab | 0.75 ± 0.1ab | 0.82 ± 0.1ab | 1.15 ± 0.1b |
Creatinine | 50.7 ± 13.0 | 68.4 ± 2.2ab | 68.5 ± 2.2ab | 70.4 ± 2.2bd | 62 ± 2.2abc | 70 ± 2.2bcd | 64.3 ± 2.2ab | 61.2 ± 2.2a |
Phosphorus | 1.54 ± 0.26 | 2.16 ± 0.06a | 2.1 ± 0.06a | 1.85 ± 0.06a | 2.06 ± 0.06a | 2.03 ± 0.06a | 1.94 ± 0.06a | 1.98 ± 0.06a |
Calcium | 2.80 ± 0.03 | 2.66 ± 0.05b | 2.57 ± 0.05ab | 2.50 ± 0.05ab | 2.58 ± 0.05ab | 2.47 ± 0.05ab | 2.34 ± 0.05a | 2.57 ± 0.05ab |
∗Creatinine | 4,878.80 ± 437.58 | 4,348 ± 342.13a | 4,139 ± 342.13a | 4,157 ± 342.13a | 3,979 ± 342.13a | 4,260 ± 342.13a | 4,069 ± 342.13a | 3,019 ± 342.13b |
∗Calcium | 1.43 ± 0.082 | 1.48 ± 0.19a | 1.60 ± 0.19a | 1.80 ± 0.19a | 1.32 ± 0.19ac | 1.93 ± 0.19ab | 1.83 ± 0.19a | 1.61 ± 0.19a |
∗Biochemical parameter in urine. Others parameters were analyzed in blood. AST, ALT, and FAS are expressed in IU/L, and glucose, cholesterol, triglycerides, phosphorus, and calcium are expressed in mmol/L and creatinine in μmol/L. Different letters indicate significant differences (p < 0.05) between all experimental groups. Experimental groups, 1, Metlin; 2, Synergy 1; 3, isoflavones; 4, Metlin + isoflavones; 5, Synergy 1 + isoflavones; 6, oophorectomized rats without inulins treatment; 7, not oophorectomized rats without inulins treatment.