Table 2.
Differentially expressed genes (mapped by DAVID): MSC-17 versus UT-MSC.
| Gene symbol | Gene name | mRNA Accession | Fold change | p value |
|---|---|---|---|---|
| Upregulated genes | ||||
| MMP13 | Matrix metallopeptidase 13 (collagenase 3) | NM_002427 | 15.60 | 0.0021 |
| C3 | Complement component 3; NULL | NM_000064 | 11.56 | 0.0039 |
| LBP | Lipopolysaccharide binding protein | NM_004139 | 5.35 | 0.0031 |
| VMO1 | Vitelline membrane outer layer 1 homolog (chicken) | NM_182566 | 4.07 | 0.0022 |
| CH25H | Cholesterol 25-hydroxylase | NM_003956 | 3.99 | 0.0023 |
| IL6 | Interleukin 6 (interferon, beta 2); NULL | NM_000600 | 3.44 | 0.0083 |
| ZC3H12A | Zinc finger CCCH-type containing 12A | NM_025079 | 3.09 | 0.0010 |
| CCL2 | Chemokine (C-C motif) ligand 2 | NM_002982 | 3.08 | 0.0405 |
| ZNF253 | Zinc finger protein 253 | NM_021047 | 2.82 | 0.0010 |
| SAA1 | Serum amyloid A1 | NM_000331 | 2.72 | 0.0102 |
| CXCL6 | Chemokine (C-X-C motif) ligand 6 | NM_002993 | 2.44 | 0.0014 |
| MMP1 | Matrix metallopeptidase 1 (interstitial collagenase) | NM_002421 | 2.40 | 0.0356 |
| NFKBIZ | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; NULL | NM_031419 | 2.36 | 0.0232 |
| MIRLET7A2 | MicroRNA let-7a-2 | NR_029477 | 2.30 | 0.0031 |
| RBMY2EP | RNA binding motif protein, Y-linked, family 2, member E pseudogene | ENST00000444169 | 2.27 | 0.0278 |
| CCL8 | Chemokine (C-C motif) ligand 8 | NM_005623 | 2.20 | 0.0012 |
| STC1 | Stanniocalcin 1 | NM_003155 | 2.20 | 0.0023 |
| SFRP4 | Secreted frizzled-related protein 4 | NM_003014 | 2.19 | 0.0136 |
| SLC22A3 | Solute carrier family 22 (extraneuronal monoamine transporter), member 3 | NM_021977 | 2.15 | 0.0452 |
| TTTY11 | Testis-specific transcript, Y-linked 11 (nonprotein coding) | NR_001548 | 2.15 | 0.0252 |
| STEAP2 | STEAP family member 2, metalloreductase; NULL | NM_001244944 | 2.12 | 0.0225 |
| SCARNA18 | Small Cajal body-specific RNA 18 | NR_003139 | 2.06 | 0.0254 |
| LOC100287834 | Uncharacterised LOC100287834 | NR_028349 | 2.06 | 0.0328 |
| Downregulated genes | ||||
| RPS24 | Ribosomal protein S24; NULL | NM_001142285 | −2.01 | 0.0209 |
| LOC100133299 | GALI1870 | AY358688 | −2.03 | 0.0095 |
| POU5F1 | POU class 5 homeobox 1 | ENST00000259915 | −2.04 | 0.0129 |
| TMEM171 | Transmembrane protein 171 | NM_173490 | −2.05 | 0.0133 |
| IGLJ2 | Immunoglobulin lambda joining 2 | ENST00000390322 | −2.07 | 0.0252 |
| ITGA6 | Integrin, alpha 6; NULL | ENST00000264107 | −2.11 | 0.0109 |
| RNU7-25P | RNA, U7 small nuclear 25 pseudogene; RNA, U7 small nuclear 11 pseudogene | ENST00000516544 | −2.16 | 0.0047 |
| GTF2IRD2B | GTF2I repeat domain containing 2B | NM_001003795 | −2.20 | 0.0040 |
| SERTAD4 | SERTA domain containing 4 | ENST00000367012 | −2.29 | 0.0470 |
| TPTE | Transmembrane phosphatase with tensin homology | ENST00000415664 | −2.85 | 0.0128 |