Table 2.
Biophysical and biochemical characteristics of endothelial function from subjects with and without neurally mediated syncope
Case (n=27) | Control (n=30) | P | |
---|---|---|---|
D1, mm | 2.89±0.51 | 2.70±0.40 | 0.128 |
D2, mm | 3.29±0.50 | 2.95±0.44 | 0.008* |
FMD, % | 8.58±3.62 | 5.26±2.26 | 0.001* |
IMT, mm | 0.285±0.04 | 0.298±0.05 | 0.327 |
ICAM, ng/mL | 93.64±52.01 | 58.95±42.85 | 0.022* |
VCAM, ng/mL | 115.32±62.36 | 72.22±51.23 | 0.008* |
E-selectin, ng/mL | 39.90±4.25 | 39.93±2.87 | 0.413 |
Epinephrine, ng/mL | 0.36±0.3 | 0.76±0.55 | 0.013* |
Norepinephrine, ng/mL | 1.05±0.96 | 1.04±1.17 | 0.961 |
All variables are reported as the mean±standard deviation
P<0.05, statistically significant.
Significant differences between the groups in terms of mean scores were assessed using an independent sample t-test. D1 - Vessel diameter at rest; D2 - Vessel diameter after hyperemia; FMD - flow mediated dilation; IAM - intracellular adhesion molecule; IMT - intima media thickness; VCAM - vascular cell adhesion molecule