Table 2.
Fatty Acids | ΔLDL | ΔHDL | ΔTAG | ΔTOTAL:HDL | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | 95% CI | p-Value | β | 95% CI | p-Value | β | 95% CI | p-Value | β | 95% CI | p-Value | ||
TOTAL | |||||||||||||
SFA | MBASIC | −0.038 | −0.077; 0.001 | 0.057 | 0.005 | −0.017; 0.027 | 0.653 | −0.038 | −0.075; −0.001 | 0.042 | −0.030 | −0.075; 0.015 | 0.196 |
MADJ | −0.036 | −0.075; 0.003 | 0.068 | 0.005 | −0.017; 0.027 | 0.638 | −0.038 | −0.075; −0.001 | 0.042 | −0.029 | −0.074; 0.016 | 0.209 | |
MUFA | MBASIC | −0.012 | −0.048; 0.024 | 0.519 | 0.011 | −0.010; 0.031 | 0.306 | −0.012 | −0.046; 0.023 | 0.507 | −0.017 | −0.059; 0.025 | 0.428 |
MADJ | −0.011 | −0.048; 0.025 | 0.534 | 0.011 | −0.009; 0.031 | 0.297 | −0.012 | −0.046; 0.023 | 0.503 | −0.017 | −0.059; 0.025 | 0.430 | |
n-3 PUFA | MBASIC | −0.027 | −0.058; 0.003 | 0.075 | 0.005 | −0.012; 0.022 | 0.590 | 0.001 | −0.028; 0.030 | 0.953 | −0.017 | −0.052; 0.018 | 0.342 |
MADJ | −0.027 | −0.057; 0.003 | 0.082 | 0.005 | −0.012; 0.022 | 0.540 | 0.000 | −0.028; 0.029 | 0.981 | −0.017 | −0.053; 0.018 | 0.332 | |
n-6 PUFA | MBASIC | −0.003 | −0.034; 0.028 | 0.866 | 0.015 | −0.002; 0.032 | 0.089 | 0.009 | −0.020; 0.039 | 0.525 | −0.012 | −0.048; 0.024 | 0.504 |
MADJ | −0.003 | −0.034; 0.028 | 0.849 | 0.016 | −0.002; 0.033 | 0.074 | 0.009 | −0.021; 0.038 | 0.559 | −0.013 | −0.049; 0.023 | 0.465 | |
FEMALES | |||||||||||||
SFA | MBASIC | −0.048 | −0.110; 0.014 | 0.131 | 0.012 | −0.022; 0.045 | 0.491 | −0.053 | −0.100; −0.006 | 0.026 | −0.057 | −0.116; 0.002 | 0.060 |
MADJ | −0.047 | −0.110; 0.015 | 0.139 | 0.012 | −0.022; 0.045 | 0.484 | −0.053 | −0.100; −0.007 | 0.025 | −0.057 | −0.116; 0.002 | 0.060 | |
MUFA | MBASIC | −0.004 | −0.061; 0.053 | 0.888 | 0.020 | −0.011; 0.050 | 0.211 | −0.017 | −0.060; 0.026 | 0.430 | −0.026 | −0.081; 0.028 | 0.342 |
MADJ | −0.005 | −0.062; 0.053 | 0.876 | 0.020 | −0.011; 0.050 | 0.209 | −0.018 | −0.061; 0.025 | 0.420 | −0.027 | −0.081; 0.028 | 0.336 | |
n-3 PUFA | MBASIC | −0.030 | −0.078; 0.018 | 0.219 | 0.011 | −0.015; 0.037 | 0.406 | 0.000 | −0.036; 0.036 | 0.990 | −0.032 | −0.077; 0.014 | 0.173 |
MADJ | −0.030 | −0.079; 0.018 | 0.214 | 0.011 | −0.015; 0.037 | 0.403 | 0.000 | −0.036; 0.036 | 0.998 | −0.032 | −0.078; 0.014 | 0.169 | |
n-6 PUFA | MBASIC | −0.020 | −0.068; 0.028 | 0.409 | 0.019 | −0.007; 0.044 | 0.148 | 0.016 | −0.020; 0.052 | 0.390 | −0.026 | −0.071; 0.020 | 0.269 |
MADJ | −0.021 | −0.069; 0.027 | 0.397 | 0.020 | −0.006; 0.046 | 0.124 | 0.014 | −0.022; 0.050 | 0.446 | −0.028 | −0.074; 0.018 | 0.231 | |
MALES | |||||||||||||
SFA | MBASIC | −0.029 | −0.078; 0.019 | 0.237 | −0.002 | −0.031; 0.026 | 0.868 | −0.016 | −0.072; 0.04 | 0.577 | 0.002 | −0.066; 0.070 | 0.962 |
MADJ | −0.026 | −0.075; 0.022 | 0.282 | −0.003 | −0.031; 0.026 | 0.863 | −0.015 | −0.072; 0.041 | 0.591 | 0.003 | −0.065; 0.071 | 0.929 | |
MUFA | MBASIC | −0.021 | −0.066; 0.025 | 0.372 | 0.000 | −0.027; 0.027 | 0.975 | −0.002 | −0.055; 0.051 | 0.952 | −0.001 | −0.065; 0.063 | 0.972 |
MADJ | −0.019 | −0.065; 0.026 | 0.400 | 0.001 | −0.026; 0.027 | 0.964 | −0.002 | −0.056; 0.051 | 0.927 | −0.001 | −0.065; 0.063 | 0.968 | |
n-3 PUFA | MBASIC | −0.026 | −0.064; 0.012 | 0.181 | −0.003 | −0.025; 0.02 | 0.818 | 0.005 | −0.040; 0.049 | 0.826 | 0.001 | −0.053; 0.055 | 0.971 |
MADJ | −0.025 | −0.063; 0.013 | 0.199 | −0.001 | −0.023; 0.022 | 0.952 | 0.003 | −0.042; 0.048 | 0.891 | 0.000 | −0.054; 0.054 | 0.992 | |
n-6 PUFA | MBASIC | 0.011 | −0.029; 0.051 | 0.583 | 0.010 | −0.013; 0.034 | 0.392 | 0.001 | −0.045; 0.048 | 0.953 | 0.000 | −0.056; 0.056 | 0.991 |
MADJ | 0.013 | −0.027; 0.052 | 0.534 | 0.012 | −0.011; 0.036 | 0.299 | −0.001 | −0.047; 0.046 | 0.975 | −0.001 | −0.057; 0.055 | 0.971 |
IQR = interquartile range; %EI = % of total energy intake; MBASIC = single nutrient model adjusted for study, region, sex (not in sex-stratified models), exact age at blood sampling, BMI at 10 years, total daily energy intake at 10 years, screen-time at 10 years, fasting status at blood sampling, and lipid concentration at 10 years; MADJ = single nutrient model further adjusted for pubertal onset and parental education; Δ = change from age 10 to 15 years; Significant associations marked in bold (p-value < 0.05 for total population analyses, p-value < 0.025 for sex-stratified analyses—Bonferroni correction for multiple testing: 0.05/2).