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. 2017 Feb 20;9(2):166. doi: 10.3390/nu9020166

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of SAMC on cisplatin-induced changes in serum renal function parameters. (A) Blood urea nitrogen (BUN); (B) Creatinine; (C) Percentage change in body weight and (D) Relative weight of kidneys in different experimental groups. SAMC was administered intraperitoneally at three different doses i.e., 10 mg/kg, 20 mg/kg and 30 mg/kg for 20 consecutive days and a single dose of cisplatin (7 mg/kg, intraperitoneally) was administered on the 15th day. On the 20th day, serum levels of BUN and creatinine, percentage change in body weight and relative weight of kidneys were recorded. Values are expressed as mean ± SEM (n = 6). ** p< 0.01 vs. control, ^# p< 0.05 vs. cisplatin.