Fig. 4. Lack of VDR is associated with down regulation of SIRT1 in VDR-M mice.
A. Protein blots of renal tissues (n=4) of control and VDR-M mice were probed for SIRT1 and the same blots were reprobed for GAPDH. Representative gels in duplicate are shown.
B. Protein blots of renal tissues of control (n=4) and VDR-heterozygous (h) (n=5) were probed for SIRT1 and reprobed for GAPDH. Gels are displayed.
C. Densitoemetric data (SIRT1/GAPDH) of protein blots of Fig. 4B are shown as bar graph.
*P<0.05 compared with FVB/N