Fig. 2.
Metabolites (μmol/g) measured by 1H MRS in tumour extracts at day 21 from MMTV-NEU-NT tumour-bearing control mice and mice treated with β-OHB (500 mg/kg), injected ip daily for 3 weeks. a Branched chain amino acids, glutamine and glycine,** p < 0.005, * p < 0.05. b Lactate and glucose. c Choline-containing metabolites: choline, phosphocholine (PC), total of choline + phosphocholine; creatine containing metabolites: creatine (Cr), phosphocreatine (PCr), ratio of PCr/Cr. * p < 0.05 (D) β-OHB and acetate; amino acids alanine, aspartate and glutamate; succinic acid and myo-inositol. Control: N = 22 tumours (13 mice); Treated: N = 33 tumours (19 mice), *p < 0.05. d other metabolites