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Functional requirement of BRD4 for poly(I·C)-induced IFN-I and -III and ISG expression. (A) Q-RT-PCR of IFNβ, IL-29, and ISG-54 and -56 in BRD4-silenced hSAECs in response to poly(I·C). **, P < 0.01 compared with control siRNA. (B) Q-RT-PCR of IFNβ, IL-29, and ISG-54 and -56 in JQ1-treated cells in response to poly(I·C). **, P < 0.01 compared with mock treatment (vehicle).
