. 2017 Feb 28;91(6):e02100-16. doi: 10.1128/JVI.02100-16

TABLE 2.

Sequence and structural similarity of capsid proteins of selected dicistroviruses, iflaviruses, and picornaviruses

Family	Genus	Virus	RMSD (Å) of superimposed Ca atoms of the respective 3D structures (top) or % identity between the respective virus coat protein sequences (bottom)^a
Family	Genus	Virus	BQCV	TrV	CrPV	IAPV	PV1	CVB3	EV71	HRV16	FMDV	ERAV	TMEV	MEV	SVV1	AiV	HAV	HPeV-1	SBPV
Dicistroviridae	Cripavirus	BQCV		1.9	1.8	2.4	2.6	2.6	2.6	2.6	2.6	2.7	2.8	2.6	2.8	2.6	2.5	2.6	2.1
		TrV	33		1.9	2.0	2.3	2.3	2.3	2.4	2.8	2.5	2.5	2.4	2.7	2.5	2.2	2.4	2.0
		CrPV	29	29		2.1	2.6	2.5	2.7	2.5	2.7	3.0	2.8	2.7	3.2	2.6	2.6	2.7	2.2
	Aparavirus	IAPV	24	23	24		2.6	2.6	2.6	2.8	3.0	2.5	2.6	3.0	2.5	2.6	2.2	2.4	2.1
Picornaviridae	Enterovirus	PV1	14	16	13	11		1.0	1.1	1.0	1.7	1.8	1.5	1.5	2.3	2.6	2.1	2.1	2.3
		CVB3	14	16	13	11	56		1.1	0.9	1.9	1.8	1.6	1.6	1.9	1.9	2.1	2.4	2.5
		EV71	13	16	13	12	45	48		1.1	1.9	1.7	1.7	1.7	1.8	2.5	2.1	2.2	2.2
		HRV16	14	15	14	9	49	49	45		2.1	2.0	1.6	1.6	2.0	2.1	2.0	2.3	2.3
	Aphthovirus	FMDV	13	15	13	12	26	26	27	23		1.6	1.6	1.5	1.6	1.9	2.1	2.7	2.6
		ERAV	17	18	17	11	24	26	23	26	36		1.9	1.6	1.9	2.0	2.4	2.6	2.8
	Cardiovirus	TMEV	19	15	14	13	29	29	30	27	31	33		0.9	1.4	1.9	2.0	2.1	2.3
		MEV	18	16	15	12	29	29	30	30	30	35	65		1.3	1.7	2.1	2.1	2.3
	Senecavirus	SVV1	15	12	11	14	29	25	29	25	30	31	38	40		1.8	2.0	2.2	2.4
	Kobuvirus	AiV	16	14	16	16	24	21	26	24	19	25	28	27	28		2.1	2.2	2.3
	Hepatovirus	HAV	17	21	16	14	18	19	17	19	17	18	21	19	20	17		2.1	2.1
	Parechovirus	HPeV-1	16	16	17	15	17	13	17	11	17	18	20	21	18	20	18		2.2
Iflaviridae	Iflavirus	SBPV	17	21	19	19	16	15	14	14	15	16	16	16	14	21	18	17

For RMSD, the distance cutoff for inclusion of residues in the calculation was 3.8 Å. Capsid protein protomers corresponding to icosahedral asymmetric units consisting of subunits VP1 to VP4 were used in the comparisons. The program Coot was used for superposition of the molecules (69). For percent identity between the respective virus coat protein sequences, gaps were ignored in the calculations. Abbreviations: poliovirus 1 (PV1), coxsackievirus B3 (CVB3), human rhinovirus 16 (HRV16), foot-and-mouth disease virus (FMDV), equine rhinitis A virus (ERAV), Theiler's encephalomyelitis virus (TMEV), mouse encephalomyelitis virus (MEV), Seneca Valley virus (SVV1), Aichi virus (AiV), hepatitis A virus (HAV), and human parechovirus 1 (HPeV-1).