FIG 1.

Schematic diagram of recombinant chimeric VSVs. The top diagram, VSV, shows the gene sequence and relative gene size of normal VSV. Below that are schematics of the chimeric virus genomes with the VSV glycoprotein gene (green) deleted and replaced with the glycoprotein genes from chikungunya virus (yellow), influenza virus H5N1 (orange), and Nipah virus F (red) and G (blue) and VLV, in which only the VSV glycoprotein gene is used and all other VSV genes are deleted and replaced by the Semliki Forest virus nonstructural protein genes (pink). VSVΔG-Nipah F+G is the combination of VSVΔG-Nipah F and VSVΔG-Nipah G.