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VLV in brain and culture. (A) After intracranial inoculation, VLV infects mostly neurons. The arrows show a dendrite stretching toward the outer cortex filled with small vesicles, a typical sign of early infection. Bar, 10 μm. (B) Two infected cells in the cortex, with vesicle-like labeling of the cell body and processes (arrows). Bar, 4 μm. (C) In vitro, both astrocytes and neurons are infected by VLV. Bar, 9 μm.
