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. 2017 Feb 21;23:938–947. doi: 10.12659/MSM.902267

Table 2.

Clinicopathological features and expression levels of PTEN, MLH1, DNMT3B in endometrial carcinoma.

Variable DNMT3B PTEN hMLH1
Normal Overexpress Loss Normal Loss Normal
Ethnic group Han 43 49 40 52 23 69
Uygur 18 44 40 22 10 52
P 0.001 0.010 0.188
Histological type ECs 37 65 59 74 23 79
NECs 24 28 21 31 10 42
P 0.236 0.040 0.635
Grade (ECs) Low 23 26 30 19 13 36
High 14 39 29 24 10 42
P 0.031 0.506 0.355
Myometrial invasion* <1/2 43 56 53 46 24 75
≥1/2 11 26 18 19 7 30
P 0.146 0.612 0.510
Lymph node metastases** No 28 46 35 39 14 60
Yes 3 10 8 5 2 11
P 0.305 0.344 0.762
Vessel invasion* No 45 65 56 54 27 83
Yes 9 17 15 11 4 22
P 0.555 0.533 0.317
Stage* I–II 46 67 59 54 26 87
III–IV 8 15 12 11 5 18
P 0.597 0.997 0.895
ER Negative 20 37 28 29 11 46
Positive 41 56 52 45 22 75
P 0.379 0.591 0.621
PR Negative 22 38 29 31 15 45
Positive 39 55 51 43 18 76
P 0.551 0.473 0.388
*

136 patients received hysterectomy;

**

87 patients received lymphadenectomy.