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. 2017 Mar 1;50:450–461. doi: 10.1016/j.actbio.2016.12.016

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© 2016 Elsevier Ltd. All rights reserved.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 5 — Expression of chondrogenic and osteogenic differentiation markers in adipose-derived stem cells (ADSCs) grown in control and differentiation (indicated by “D”) media on plasma modified scaffolds. Gene expression assessed by RT-qPCR at 21 days. of culture is shown. A) Expression of aggrecan and collagen type II following ADSC chondrogenic differentiation; upon differentiation both transcripts are significantly higher on the COOH scaffolds than on the other scaffolds. B) Expression of alkaline phosphatase (ALP), collagen type I and osteocalcin following ADSC osteogenic differentiation; upon differentiation gene expression increase is greater on NH₂ modified scaffolds than on the other scaffolds (^∗p < 0.05).