Table 2. . Type I error of Sobel test for indirect effect for simulation scenario I assuming sensitivity = (0.70, 0.80, 0.90, 0.95), and specificity = 1.

	True†	SN = 0.70	SN = 0.8	SN = 0.9	SN = 0.95
H0 (β1b = 0, ϑ2c = 0)	0%	0%	0%	0%	0%
H0 (β1b = 0, ϑ2c = 0)	4.9%	27%	18%	10%	6.5%

^†Type I error of Sobel test when the true exposure is used in the regression analyses.

^‡Exposure–mediator association from Equation 3.

^§Mediator–outcome association from Equation 2.

SN: Sensitivity.