Table 1. . Cord blood and placental DNA methylation distributions according to the Illumina annotation functional categories.
| Annotation category | n |
Hypomethylated status (β < 0.3) (%) |
Hypermethylated status (β > 0.7) (%) |
Methylated status (β ≥ 0.5) (%) |
|||
|---|---|---|---|---|---|---|---|
| Cord blood | Placenta | Cord blood | Placenta | Cord blood | Placenta | ||
| All probes |
358,940 |
40.6 |
35.0 |
41.5 |
23.8 |
48.0 |
34.3 |
| Island |
118,945 |
79.3 |
68.2 |
11.8 |
6.6 |
13.8 |
10.1 |
| Shelf |
32,537 |
7.0 |
5.8 |
72.4 |
46.5 |
82.2 |
62.3 |
| Shore |
86,626 |
42.0 |
35.2 |
33.8 |
19.8 |
41.4 |
30.2 |
| Other |
120,832 |
10.5 |
10.0 |
68.0 |
37.6 |
77.3 |
53.4 |
| Enhancer |
79,889 |
24.6 |
18.8 |
51.8 |
29.2 |
60.4 |
43.7 |
| Not enhancer |
279,051 |
45.2 |
39.6 |
38.6 |
22.3 |
44.5 |
31.5 |
| Promoter |
25,921 |
88.3 |
83.5 |
6.6 |
4.7 |
7.6 |
7.0 |
| Not promoter | 333,019 | 36.9 | 31.2 | 44.3 | 25.3 | 51.2 | 36.4 |