Table 1. Summary of top hits for each shape, YAP/TAZ ratio, and total YAP/TAZ for LM2 ONTARGETPlus and siGENOME screens.

	Gene Name	Gene ID	LM2 ONTARGETPlus		LM2 siGENOME
			Fold Change	Z-score	Fold Change	Z-score
Top hits were chosen from the ONTARGETPlus library. Hits considered to be common across siRNA libraries are denoted by an asterisk.
Spindly	FAM13A	10144	3.13	10.6	2.61	6.97*
Large, spread	ECT2	1894	7.25	16.0	7.66	11.6*
Triangular	TRIO	7204	1.46	3.35	1.65	2.66*
Fan	TRIO	7204	2.58	3.29	1.27	1.13
Small, round	ARHGAP5	394	2.35	8.03	1.12	0.51
YAP/TAZ ratio
High	ARHGEF15	22899	1.12	3.73	1.12	2.17*
Low	ARHGAP33 /SNX26	115703	0.48	−5.65	0.86	−2.94*
Total YAP/TAZ
High	NET1	10276	1.40	3.45	1.19	0.99
Low	MCF2	4168	0.38	−7.85	0.79	−2.38*