Table 2. Summary of top hits for each shape, YAP/TAZ ratio, total YAP/TAZ for MDA-MB-231 ONTARGETPlus and siGENOME screens.

	Gene Name	GeneID	MDA-MB-231 ONTARGETPlus		MDA-MB-231 siGENOME
			Fold Change	Z-score	Fold Change	Z-score
Top hits were chosen from the ONTARGETPlus library. Hits considered to be common across siRNA libraries are denoted by an asterisk.
Spindly	DOCK5	80005	2.78	8.70	1.62	2.57*
Large, spread	ECT2	1894	5.47	7.83	8.64	10.7*
Triangular	MCF2	4168	1.54	5.14	0.97	0.40
Fan	ECT2	1894	3.15	6.98	3.02	7.58*
Small, round	ARHGEF18	23370	1.57	4.01	0.48	−4.45
YAP/TAZ ratio
High	PIK3R2	5296	1.67	5.67	0.85	−1.34
Low	MYO9B	4650	0.62	−3.39	0.73	−2.84*
Total YAP/TAZ
High	FARP1	10160	1.31	1.93	1.60	4.19*
Low	PIK3R2	5296	0.61	−5.46	0.74	−3.41*