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. 2017 Mar 1;4:170022. doi: 10.1038/sdata.2017.22

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0 Metadata associated with this Data Descriptor is available at http://www.nature.com/sdata/ and is released under the CC0 waiver to maximize reuse.

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(a) siRNA (negative control) (b) siRNA knockdown of vWF (positive control). Nuclei (blue), trans-Golgi network (green), WPB (red) and plasma membrane (grey) were stained in HUVEC cells. Scale bar 20 μm. The figures show representative, cropped regions of fields of view, that allowed the proper visualization of the small WPBs. (c) The intensity Z scores (3_TotalWPBrawIntDenPerCellNR) of negative control wells (siCTRL) are significantly higher than that of positive control wells (siVWF). Mean±S.D. plotted for 88 independent biological replicates for each condition, two-tailed Student’s two sample t-test P<2.2e-16.