Table 1.

Odds ratios and probabilities for CNA evolution (CE) based on clinical parameters as calculated by binary logistic regression.

	Odds Ratio	p-Value	95% Confidence Interval	Probability for CE if Characteristic present	Probability for CE if Characteristic absent
IgHV
IgHV unmutated (N = 63/84)	1.142	0.797	0.414–3.146	0.413	0.381
High-risk Genomic Abnormalities at Trial Enrollment
TP53 Loss and/or Mutation (N = 14/86)	1.667	0.384	0.527–5.270	0.500	0.375
ATM Loss and/or Mutation (N = 34/86)	1.12	0.801	0.463–2.707	0.412	0.385
Treatment Arm
FCR (N = 40/86)	2.806	0.024	1.149–6.851	0.525	0.283
Response
Complete Response (N = 16/84)	1.720	0.333	0.574–5.152	0.500	0.368
Non-response (N = 10/84)	0.629	0.525	0.150–2.626	0.300	0.405