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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Ann Biomed Eng. 2016 Sep 13;45(3):644–655. doi: 10.1007/s10439-016-1725-0

FIGURE 7.

FIGURE 7

Significant time-dependent differences in proliferative density within both the intima and media are observed (p<.001). (A) In the intima, overall proliferation initially peaks at Day 7 and returns to baseline quiescent levels by Day 28. Consistent with the subsequent difference in intimal growth rates, enhanced proliferation was observed in the low flow grafts one week following implantation (Day 7: *p<.001 low vs. intermediate, p<.001 low vs. high flow). (B) In contrast, the medial compartment demonstrated a Day 3 peak in proliferative density, which was independent of the imposed flow condition.